Medicon Publications

Introduction: Neonatal meningitis is a medical emergency having consistently high rate of mortality and morbidity in spite of leveled up vaccination, increased institutional deliveries with intrapartum prophylactic antibiotics and asepsis, and good hospital practices.
Material and Methods: Total 718 neonates were enrolled. CSF samples were cultured and read at 24, 48 and 72 hours. WBC Count of CSF of 30 / mm³ was considered cutoff to rule out possible contamination. Culture positive isolates were identified by MALDI-TOF VITEK MS. Antimicrobial susceptibility pattern was noted. PCR was done for atr gene of Streptococcus agalactiae of all culture negative samples.
Result: Out of 718 neonates enrolled 73 CSF were culture positive and 645 cultures were sterile. 5 isolates were probable contamination. Total 68 samples were positive with 63 bacterial isolates and 5 Candida species. Most commonly isolated bacteria were Acinetobacter spp (42%). and Klebsiella pneumoniae (15.9%). Among fungal isolates Candida albicans (4.4%) and Candida parapsilosis (2.9%) were isolated. PCR detected 2 cases of Streptococcus agalactiae causing meningitis.
Conclusion: Percentage positivity of bacterial and fungal meningitis was found to be 9.1 % and 0.7% respectively. Out of 68 samples, 51 had Gram negative and 12 had Gram positive bacteria on culture. Fungal isolates grew in 5 samples. Rare organism like Elizabethkingia anophelis (2.9 %), Chryseobacterium indologenes (2.9 %) Aerococcus viridians (1.4%) were isolated. PCR detected 2 cases of Streptococcus agalactiae (atr gene) of bacterial meningitis. Streptococcus agalactiae being a common etiology, had not been isolated in our cultures.
Keywords: Neonatal meningitis; Etiology; Antimicrobial Susceptibility Pattern; Risk Factors

The main advantage of systematic review (SR) over other review types, such as narrative review, is its transparent and rigorous approach to minimize bias and ensure future replicability. Reproducibility, comprehensiveness, and transparency are the 3 keys to minimize bias. Reproducibility and transparency are deemed more important than comprehensiveness as missing literature may be identifiable from a reproducible and transparent SR lacking comprehensiveness but missing literature cannot be identified from a comprehensive SR lacking reproducibility and/or transparency. Hence, a SR lacking reproducibility and/or transparency is a narrative review. Several studies on published SRs report poor reproducibility and transparency. Here, we examine a sample of 100 SRs published in 2023 and indexed within PubMed for reproducibility and transparency on 10 criteria - 7 for reproducibility and 3 for transparency. In terms of reproducibility, our results show that only 31 SRs gave sufficient information for reconstructed searches in PubMed to yield search results within 10% of the hits reported. In terms of transparency, none of the SRs provided the full list of search results and only 5 SRs provided sufficient information to determine which study is excluded by which exclusion criterion. Hence, our results support previous studies reporting poor reproducibility and transparency in SRs. We propose that search URLs should be given whenever possible, and the full list of search results with inclusion / exclusion analysis should be given in all cases.

Haqua Revitalize^® Therapy (HART) has significant effects on the psychological processes of the human body, enhancing emotional well-being. Here are some keyways in which HART influences psychological processes:
     Emotional health, one of the Five Aspects of Health (FAH), plays a crucial role in our overall well-being. It revolves around how individuals manage and cope with their emotions in response to the incidents and challenges they face in daily life. Emotional well-being, also referred to as emotional health or wellness, is a key component of our overall health and quality of life [23].

Background: Cancer is commonly associated with depression and depressive symptoms. Depressive disorders often worsen over the course of cancer treatment, persist after cancer therapy, recur with the recurrence of cancer and impact on function and medical outcomes. We aimed at assessing whether depression management could happen at the cancer center without referral to the mental health clinic.
Methods and materials: We conducted a quasi-experimental study for screening and treatment of depressive symptoms among patients living with cancer, who were attending oncology services at Kamuzu Central Hospital between May, 2021 and August, 2022. The intervention arm had screen and treat for depressive symptoms as an integrated approach to cancer care within the study site while the comparison arm had screen and refer patients diagnosed with depressive symptoms to usual mental health clinic. Patients were followed-up for six months and health related quality of life was measured using Euroqol-5 dimession-3 levels tool during each visit. Depressive symptoms were evaluated using the Patient Health Questionnaire-9.
Results: There were 214 participants in the study; 112 in the comparison and 102 in the intervention group. The majority (65%) were females and at least 36% of the participants were in the middle age group (26-45 years); 29% of the participants had unknown HIV status. Participants of high socio-economic status were twice more likely to report poor quality of life than those with lower socio-economic status 1.99 (95% CI: 1-12-3.53, p<0.02). Employed participants were less likely to report poor quality of life 0.62 (95% CI: 0.42-0.90, p<0.01). Poor quality of life was steadily declining with each successive clinic visit, 0.07 (95% CI: 0.05-0.10, p< 0.001) and there were similar patterns of improvement in quality of life between study arms, 1.06 (95% CI:0.73-1.54, p<0.77).
Conclusion: Depression screening and treatment could be integrated within the cancer care for improved quality of life in Malawi. While persons accessing care within hospital can benefit from HIV testing and referral for treatment if found HIV positive, Malawian cancer patients at Kamuzu Central Hospital might not have benefitted from these services as a handful of participants in our study had not been tested.
Keywords: Quality of life; Cancer; Depression

Background: Depression is one of the most common mental health disorders in patients living with cancer worldwide. An understanding of the prevalence of depressive disorders among this sub-group of patients should inform both its prevention and management. There is currently little evidence on correlates of depressive disorders amongst the persons living with cancer in Malawi. Therefore, we conducted this study to estimate prevalence and correlates of probable major depressive disorder among patients living with cancer at a National Cancer Center based at Kamuzu Central Hospital (KCH), Lilongwe in Malawi.
Methods: We utilized a cross-sectional design nested in a larger quasi-experimental study which was evaluating the effect of integrating depression screening and management on clinical outcomes among patients living with cancer who were attending oncology services at Kamuzu Central Hospital in Lilongwe. A validated PHQ-9 tool was used to estimate prevalence and correlates of probable major depressive disorder. A total of 399 consented participants were enrolled from August to December, 2021.
Results: The study comprised more females (64%). Cervical cancer (33%), Kaposi’s Sarcoma (16%), breast cancer (9%) and esophageal cancer (4%) were the top four common malignancies in the study. At least 55% of the study participants had depressive symptoms. The prevalence of probable major depressive disorders was 11.5 %; most (52%) of whom had moderate depressive symptoms on PHQ-9 scale. Patients supported by palliative care were associated with reduced odds of major depressive disorders 0.36 (95% CI: 0.14-0.94).
Conclusion: A high proportion of patients living with cancer had probable major depressive disorder. Patients supported by palliative care had reduced odds of probable major depressive disorder. There was need to integrate screening and management of depressive disorder as well as palliative care services among patients during routine cancer care in Malawi.
Keywords: cancer; prevalence; depression; Patient Health Questionnaire

It was the middle of August 2023, a fine Sunday afternoon in Brooklyn. Running around with my fellow international medical students in Dr. Hameed’s office, taking history, participating in patient care, and trying to soak up the essence of the American healthcare model, we were waiting for Dr. Moskowitz to come to the office for our research undertakings.

This research includes the effects of preharvest 1-Methylcyclopropene (1-MCP) (Harvista) treatments on fruit drop, fruit quality and harvest maturity of ‘Pink Lady- Cripps Pink’ apple cultivar. The research had materialized in 2016 and 2017. For this purpose, preharvest 1-Methylcyclopropene treatments at doses of 50, 100, 150 and 200 g ha^-1 were applied to ‘Cripps pink’ apple cultivar in Çanakkale, Lapseki region, Turkey. Samplings collected from trees at application day and 7, 14, 21 and 28 days after applications respectively. Fruit drop rate, flesh firmness, soluble solids content, starch degradation, titratable acidity, skin color, and ethylene production were evaluated after each sampling date. Furthermore, fruits were kept at 20-22°C temperature and 50-60% relative humidity conditions for 7 and 14 days as shelf life to determine the changes in quality assessments. According to the results, Harvista applications with 150 and 200 g ha^-1 doses were found out as the most positive applications because of preventing fruit drop and minimizing the changes of quality parameters. Harvest maturity could be prolonged for 21 days with these application doses.
Keywords: Cripps pink; 1-Methylcyclopropene; fruit drop; quality parameters; shelf life

In the last two or three years, farmers have faced extremely challenging circumstances, particularly in the mango industry. This is because of climate change, specifically storms or cyclones, which have severely damaged mango crops during the pea-sized fruiting and flowering stages in Gujarat. As a result, farmers have lost a significant amount of mango yield and their financial worth. Mango cultivation entails several challenges, as evidenced by the fact that nearly every variation exists. Mango production is eventually losing money for farmers owing to factors such as alternate bearer, limited shelf life, major or minor diseases, and lack of resistance to climate change. For over two or three years, the sonpari variety of mango has gained widespread popularity among consumers because of its outstanding flavour, resistance to disease, pests, and disorders, and ability to withstand harsh weather conditions.

Over the last decade, green synthesis methods for biochar-supported metallic nanoparticles have gained popularity due to their versatile applications in technology. Addressing concerns about microorganism contamination in wastewater, nano zero-valent iron (nZVI) within biochar (BC) inhibits bacteria through reactive oxygen species and interacting with bacterial membranes. This study examines two distinct materials: rice husk (RH) and lignin (Lig), for the synthesis of nZVI. RH was explored via two routes: (1) Synchronous route where iron salt was loaded into raw RH feedstock, followed by pyrolysis at 300 °C and subsequent carbothermal reduction (CR) of iron at 900 °C (BM-nZVI), and (2) Asynchronous, involving iron salt loading onto pre-pyrolyzed RH-BC with subsequent CR (BC-nZVI). For Lig, the study examined: (1) Synchronous route with nZVI deposition on pre-pyrolyzed (1000 °C) Lig-BC, creating surface-deposited nZVI (Lig-s-nZVI), and (2) Asynchronous route by mixing iron salt with dissolved feedstock to embedded nZVI in a carbonaceous carrier, resulting in engraved nZVI (Lig-eG-nZVI). The characterization of synthesized nZVI particles was obtained by SEM analysis. This study shows to comparatively evaluate the biological responses of Staphylococcus aureus (S. aureus) to four variations of BC-supported nZVI materials including the pristine BC of each material serving as the control. Initially, pure bacterial cultures were employed to measure inhibition zones using the well diffusion method, revealing prominent inhibition zones for RH-nZVI, while no significant inhibition was observed for Lig-nZVI and pristine BC. The minimum inhibitory concentration of RH-nZVI against S. aureus was determined to be 0.02 g mL^-1, and optical density at 600 nm (OD₆₀₀) was assessed. By contrast, BC-nZVI reached higher levels of microbe inactivation than BM-nZVI due to the FeC4 layers surrounding nZVI particles, potentially hindering BM-nZVI's reactivity. Testing was conducted on hospital and farm wastewater. Gel electrophoresis, Gram's staining, and catalase test were used to identify microbes in wastewater.
Keywords: Antimicrobial activity; wastewater; lignin biochar supported nZVI; rice husk biochar supported nZVI; Staphylococcus aureus

The article dedicated to finding measure of compactness of normalized dataset, and analyze dataset with using compactness. For finding measure of compactness, we search for hidden regularities from “jaw” database. In this way we need consider n-p full task and it will be 2ⁿ combinations. To solve this task, we use heuristic way with using binary matrix. In the article, we use various methods which find normalization of dataset. Our experiments were taken from “jaw” and we obtained a result from this dataset.
Keywords: object; set; class; feature; nominal; quantitative; space; similarity matrix

When considering the entire history of science, DNA sequencing is still a relatively new process. Here, we take a quick look at its potential in a few current and developing fields.
Developmental biology
Each of us begins as a single cell and grows into a highly ordered mass of billions of cells. But our knowledge of development is still incomplete. Sequencing-based, scalable single-cell profiling is made possible by recent technology. While ex vivo methods, such as single-cell RNA-seq, are widely used, one unconventional method involves performing RNA or protein sequencing in situ, which preserves the spatial context. Other cutting-edge techniques utilize transport barcodes to catalogue neural connections or in vivo editing of the genome to monitor cell-lineage associations. DNA editing may be used to document biological events more broadly, such as tracking calcium levels or gene expression.

This article introduces CiesMap software, developed in Visual Studio 2022, designed to collect and manage information about photovoltaic systems (PV systems) in Cuba. It was applied in the diagnostic assessment of PV systems in the municipality of Guamá, Santiago de Cuba. CiesMap enables the recording of technical data such as location, generation capacity, and operational status of PV systems. Using an interactive satellite view through the GMap control, the software facilitates the identification of settlements and PV systems with color-coded markers. Moreover, CiesMap integrates with an Access database for storing and monitoring PV system information. This tool optimizes energy resource management, enhances strategic planning, and facilitates data-driven decision-making, thereby improving the operational efficiency of PV systems.
Keywords: CiesMap; Visual Studio; Database; C#; Photovoltaic Systems

Aluminum alloys have received wide attention in the field of industry in recent times due to their lightweight, high resistance to corrosion, and ease of formation. In addition to their availability and affordability, the problems that occur in the welding of aluminum by traditional methods make the friction stir welding process one of the most important welding processes. This solid-state welding process was discovered in 1991 by TUW and is widely used in the welding of dissimilar aluminum alloys. In our research, we welded two important aluminum alloys in the industry (A7075/AA6061) with a thickness of 3mm. We changed some welding process parameters, including tool pin length, feed rate, and rotational speed. After placing an alloy (AA 6061) in the advanced side and tilting the tool, we examined the welded samples to find out the effect of the aforementioned parameters on the tensile strength and resulting hardness. We found that the length of the tool pin has the greatest influence on these properties, as they increase with the increase in the length of the pin. We also noted that the rotation speed and feed rate have a joint effect on the mechanical properties. The highest hardness was obtained at feed rates of 20 and 45 mm/min and rotational speeds of 1200 and 900 rpm, respectively. The highest tensile strength of 209 Mpa was obtained at a rotation speed of 1200 rpm and a feed rate of 20 mm/min.
Keywords: Friction stir welding; pin length; AA7075 and AA6061 aluminum alloys

The global warming, which is driven by the human activities and increasing concentrations of greenhouse gases viz. CO₂ and methane, poses significant risks worldwide. These risks include but are not limited to the rising levels of the oceans, disruptive weather conditions, and chaos to ecosystems and biodiversity. These changes are severe threat to the natural environments, health of human and animal kingdom, food security, and economic stability (IPCC, 2021).

Having worked in the United Arab Emirates (UAE) for over a decade, specializing in sustainability and environmental projects, I have observed the transformative impact of landscaping construction on addressing these challenges. My involvement in some of Dubai and Abu Dhabi’s largest greenery and park projects has provided insights into how strategic landscaping can help mitigate global warming.

Large language models (LLMs) are revolutionizing the way we interact with information. But these powerful tools do not operate in a vacuum. We need instructions to guide LLMs towards the desired outcome. This is where prompt engineering comes in. LLMs are trained on massive datasets of text and code. While this imbues them with vast knowledge, it doesn't guarantee they will understand our specific requests. A poorly written request can send the LLM into a rabbit hole, resulting in meaningless or irrelevant text.

In spite of the budding interest of researchers, policymakers and practitioners, there are still differing and disjointed conceptualizations of sustainable regional and trans-border infrastructure (SRTBI) as its meadow is still emerging. In an effort to fill this research gap, this study reviews and synthesizes SRTBI research to identify core publication vents and papers, key theoretical and methodological approaches, and key variables of interest that exist in the SRTBI literature, and provides directions for future research.

Chemical-enhanced oil recovery (EOR) represents a pivotal technology in the petroleum industry, aimed at maximizing the extraction of hydrocarbons from reservoirs. Traditional oil recovery methods typically leave a substantial portion of the oil in the reservoir, making EOR techniques crucial for boosting extraction efficiency. Among the various chemical EOR methods, polymer flooding stands out due to its ability to improve the viscosity of the displacing fluid, thus enhancing the sweep efficiency and reducing the mobility ratio. This manuscript explores the application of polymeric composites in chemical EOR, highlighting their formulation, mechanisms, advantages, challenges, and recent advancements.

A major threat for the agriculture is to feed ever increasing global population, simultaneously need for decreasing the environmental effect and conserving natural resources for the coming generations. Agriculture impacts on environment negatively and positively. But the negative impacts are so serious as pollution and deterioration in soil, water, and air. The agriculture has also beneficially effect on environment as carbon sequestering in food crops and soils or reducing flood threats by following some sustainable farming practices. The Organization for Economic Cooperation and Development checking relationship among the environment and agriculture recognized policies for agriculture, which are beneficial to reduce the harmful effects on environment while increasing the beneficial impacts and gives the direction to enhance policy consistence of the agricultural sector for the environmental production.

This research examined the necessity of the use of the Raster calculator tool of the map algebra in ArcGis for calculating the indices for enhanced and soil adjusted vegetation indices. The values acquired will then be used to cautiously observe the growth of sugarcane from the planting stage to harvesting stage. maps will be generated, green and red colors will be used to show bad health and good health of sugarcane. Additionally, after adequate examination, it was realized that when these broad band indices are made into maps it can be used in monitoring the growth of sugarcane in these regions.
Keywords: Enhanced Vegetation Indices; Fadama

With the current world population being at 8 billion and still counting, there is an urgent need to tackle the questions in food security, which can be answered by improvements in the various crop species and their sustainable management practices. These improvements can include the production of various stress resistant crops, that cause minimal resource exhaustion. Thus, in order to produce such novel crop strains, approaches such as Nano Omics can be employed. Also, introduction of certain properties and changes in certain metabolic pathways of plants can lead to them being much more suited for sustainable agricultural practices. Omics refers to the holistic approach of studying (quantifying, localizing, characterization) of all the essential components of a biological body, such as, genes, transcripts, proteins, and metabolites. The amalgamation of this knowledge with the emerging field of nanotechnology can bring about revolutionary amendments in the field of crop improvement and crop management, that would lead to better sustainable agricultural practices and food security. Omics technology (specifically, Genomics) has already enabled the development of crops like, drought tolerant maize, Flavr savr tomato, rice with higher grain production, etc. Besides, there has also been the use of engineered nanomaterials (ENMs) in precision agriculture to improve crop quality, nutritional value, pathogen resistance, and most significantly to improve crop resilience against extreme climatic conditions. Additionally, ENMs have been used in various crop management practices and experiments to detect nano-toxicity, or as carriers or active material in nano- enabled pesticides. Hence, employing these approaches would also help in the development of agricultural practices that are both sustainable and resilient to the ever-changing climatic conditions, but what one needs to understand is the abundance of such techniques which often remain unemployed due to lack of feasibility.
Keywords: Engineered nanomaterials; Nanotechnology; Nano-toxicity; Omics; Agriculture

Hill Agroforestry Systems (HAS) are often characterized by the integration of woody perennials with other crops like cereal, pulses, vegetables and livestock on steep sloppy terrain where agrarian lands are managed through terrace farming. It forms an integration of various plant species and their interactions with other ecological components which plays a crucial role in sustainable land-use management and environment conservation. Usually in hilly regions, farming is predominantly of subsistence type. Due to rough terrain and harsh climatic conditions, fear of human animal conflict and poor soil productivity, farmers here often face challenges while maintain their farmlands and the livestock.

Adopting climate-resilient agriculture practices can indeed enhance income security by mitigating the risks posed by climate change. It involves implementing strategies that help farmers adapt to changing climate conditions, such as droughts, floods, and extreme temperatures. These practices can include crop diversification, improved water management, soil conservation, and the use of resilient crop varieties. By adopting such practices, farmers can better protect their crops and livelihoods against climate-related risks, ultimately leading to improved income security.
Climate-resilient agriculture refers to practices, technologies, and systems that help agriculture adapt to and mitigate the impacts of climate change. These approaches aim to maintain or increase agricultural productivity while enhancing the resilience of farming systems to climate variability and extreme weather events.

As the global population rapidly grows to 10 billion by 2050, the need for sustainable and efficient food production has never been pressing. The most recent statistics indicates that, global aquaculture production hit a record-breaking 130.90 million tons in 2022 (SOFIA, 2024). The aquaculture sector, which is already indispensable in providing global food demands, is facing growing challenges, including rising feed costs, pollution, and the need to reduce its dependence on traditional fishmeal and soybean meal. In this crossroads, the arrival of insects is a boon to the industry because they represent an understated yet revolutionary subject in the quest for sustainable aquaculture. Insects, particularly black soldier flies (Hermetia illucens) and mealworms (Tenebrio molitor) have emerged as strong options for inclusion in aqua feeds (Singh et al., 2023). Their protein content is comparable to fishmeal, indicating a remarkable amino acid profile required for aquatic animals' growth and health. According to studies, insect protein can effectively substitute up to 50% of fishmeal in diets for a number of fish species without affecting growth performance or feed efficiency (Siddaiah et al., 2023). This substitution not only reduces pressure on wild fish species, but also promotes to create a more balanced and resilient food system. Furthermore, insects are not only a feasible protein source; they are also high in lipids, vitamins, and minerals, which boost the nutritional content of aqua-feeds (Ardra et al., 2024). The inclusion of them in fish diets has been related to improved intestinal health, disease resistance, and even better quality products in terms of flavour and texture. As research reveals the many benefits of insect-based feed, the potential for wider adoption in the industry grows tremendously.

Objective: To study the immediate and long-term results of revascularizing osteotrepanation and lumbar sympathectomy in patients with critical ischemia of the lower extremities (CILE) on the background of distal arterial steno-occlusion.
Material and methods: The results of standard treatment and the use of various types of indirect revascularization in 171 patients with CILE against the background of distal arterial steno-occlusion were analyzed. The etiological factors of CILE were obliterating atherosclerosis (115 patients) and thromboangiitis obliterans (56 patients). The level of arterial damage: femoropopliteal segment -26 (15.2%), popliteal-tibial segment -56 (32.7%), tibial-foot segment -50 (29.2%), foot - 25 (14.6%), multilevel lesion -14 (8.2%). To establish a diagnosis and assess the results of treatment, changes in the clinical status of patients were traced, Doppler ultrasound with angioscanning, multispiral computer-tomographic angiography, rheovasography were performed, and skin oxygen saturations were determined. The immediate results of treatment were assessed by the Rutherford R.B. et al. (1997) scale.
Results: 48 patients (control group) underwent standard treatment. The following types of indirect revascularization were performed to stimulate regional circulation: revascularizing osteotrepanation (ROT) in 64 patients, lumbar sympathectomy (LSE) in 59 patients. In patients with CILE against the background of distal arterial steno-occlusion, ROT and LSE improve the immediate and long-term results of surgical treatment, make it possible to preserve the supporting function of the limb, reduce the frequency of rehospitalization, and continue an active lifestyle.
Conclusions: Correlation and statistical analysis revealed a significant dependence of the results obtained on the method of revascularization. The technical simplicity of performing the operation of ROT and LSE creates the prerequisites for the introduction of surgical departments of multidisciplinary clinics in daily practice.
Keywords: distal occlusion of the arteries; critical ischemia of the lower extremities; revascularizing osteotrepanation; lumbar sympathectomy

Quinoa has recently gain popularity since the declaration of International Year of Quinoa in 2013. However, there are still limited reviews on quinoa in terms of nutrition and health. Thus, the aim of this 10-year systematic review is to assess the nutritional profile and potential health benefits of quinoa. PubMed search was done on 10 January 2024 and 164 papers were identified within the past 10 years (1 January 2014 to 1 January 2024). After exclusions, a total of 35 papers were included in this systematic review. The 35 papers were categorised into three main themes: (a) effects of processing techniques, (b) potential health benefits, and (c) genotype and phenotype variation.

Objective: The Advanced Life Support in Obstetrics (ALSO) course was designed as a two-day interprofessional course to equip participants to manage various low frequency obstetrical emergencies nationally and internationally. It is used nationally by numerous Family Medicine Residency programs to improve safety in maternity care, optimize team-based care, and showcase obstetrical care by family physicians. In 2017, the course was redesigned into a one-day course, yet the outcomes of this new course design have not been examined. This study assessed non-inferiority for confidence in managing emergencies and skills before and after the single day ALSO course.
Methods: Participants completed questionnaires before and immediately following ALSO training assessing confidence managing OB emergencies: hypertensive disorders of pregnancy, malpresentations/malposition/multiple gestations, assisted vaginal delivery, shoulder dystocia, postpartum hemorrhage, and maternal resuscitation/trauma. A Likert scale was used with response choices ranging from strongly disagree (1) to strongly agree (5) for each item.
Results: Over three sessions, 69 participants received ALSO training (49 pre-surveys and 36 post-surveys completed). Of the participants, 24 (51.0%) were first year residents, 6 (12.2%) were second year residents, 5 (10.2%) were third year residents, 6 (6.1%) were attending physicians, 3 (6.1%) were nurses, 1 (2.0%) midwife, and 6 (12.2%) were medical students. Total confidence managing individual conditions increased significantly from pre- to post-survey (p<0.001).
Conclusions: The one day ALSO course demonstrates improved confidence in obstetrical emergencies immediately after the course for all conditions. It is non-inferior to the previous 2- day training course.
Keywords: Family Medicine Obstetrics; Advanced Life Support in Obstetrics

During the last decades, patient faith in physicians has declined. Doctors are distrusted for several reasons, including incorrect conclusions that had fatal consequences for patients. Doctors may have prescribed inappropriate medications which produced negative effects or didn't benefit patients. Medical blunders have sometimes occurred due to carelessness or neglecting information. Patients feel abandoned and don't know what their doctors are doing. Customers are even less trusting of the medical industry due to excessive pricing and lack of transparency. All of these things have made people more skeptical of the medical system, which has caused the doctor-patient relationship to break down. Doctors must address these challenges and regain patient trust to improve healthcare.
Keywords: doctor-patient relationship; large language model; Mind Genomics; trust in physicians

There are some nature radiations from the ground and we discuss sun light for human health as well we protect some of sun light beams. Another daily life radiation, we discuss the activated LED for health. We also discussed the water transparence of weak energy radiation like THz. We followed the radiation from the Fukushima contaminated soils, and its reduction by the activated water resulting in nuclear transformation to obtain the stable elements. From our experiments, we presume tritium to generate lithium by the nuclear transformation.

The curriculum of our medical career proposes a humanistic training model for medical students that includes as objectives: increasing their self-knowledge, personal emotional growth, cognitive and critical development, fostering the spirit of solidarity, encouraging enthusiasm and balance in their academic and then professional life (and in their entire life), and an empathetic and compassionate behavior with patients.
Different authors and scholars dedicated to humanistic training in medicine have proposed various educational models. William Branch, who can be considered a pioneer of the inclusion of humanism in undergraduate medicine, and his proposals, along with those of other authors who emphasize the value of narrative, reflection, and humanistic development integrated into clinical training, have been powerful inspirations for our program.

Anemia is one of the major leading health concerns globally and India is one of the leading countries contributing to the global burden of anemia. Anemia plays out differently depending on the group that is struggling with the condition. Women of reproductive age (WRA) are one of the most vulnerable groups to this condition and maternal anemia is associated with increased mortality. The physical diagnosis of anemia is often based on clinical signs alone such as pallor of the conjunctivae, nail beds, face, palms, and palmar creases. Anemia can also be determined by biomarker assessment which is Hb concentration. It is the most preferred biomarker for diagnosis. HemoQR is a Hb detection test kit consisting of a detection strip and a software application which enables immediate reporting and data-driven decision making. It is a point-of-care test based on a mobile application, making it user-friendly and low maintenance to be used anytime, anywhere. In this paper we have done a comparative study of HemoQR and Hematology Analyzer using 24 EDTA blood samples. The study was conducted in Patkar laboratory. The results showed 95% repeatability and 96% reproducibility for the Haemoglobin Detection Kit.