Volume 1 , Issue 3

Neurological and neurodegenerative diseases have become a major social and economic burden worldwide with more individuals predicted to be affected in coming decade. Therefore, understanding the neuropathological mechanism and identifying the promising target for intervention has become an active area of research in neurodegeneration. The chronic neuroinflammation has considered to be fundamental mechanism causing progressive loss of dopaminergic neurons as observed in clinical course of various neurodegenerative diseases. Microglial proliferation and activation are the hallmarks of several neurological disorders.

Abstract
A study to assess the knowledge, opinion of faculty and post graduate students of nursing regarding translational Research in nursing in Tirupathi was conducted on 50 nursing faculty and 50 nursing post graduate students in Tirupathi, with the objectives to find out 1. Knowledge regarding translational Research 2. Opinion regarding translational research. Method and Material It was an incidental study conducted by the investigator when nearly 500 nursing personnel came to participate in the national workshop organised by Sri Padmavathi Mahila Visva vidyalayam in Tirupathi. The study comprised of survey questionnaire of multiple choice type to elicit the information and an opinion check list. The sample of study is selected randomly from 2 groups comprised of faculty and post graduate students. The data was collected before starting of the Workshop when participants assembled for registration. Results showed that the knowledge score’s levels of nursing faculty was almost the same as that of post graduate nursing students. However, both groups showed slightly different responses on opinionnaire regarding translational research. Conclusion Translational research in nursing is not a myth and distance dream but can be a realty.

Keywords: Nursing; Evidence Based Practice; Nursing Education; Nursing Research; Translational Research; Knowledge and Opinion

Evaluation of Smile Components in Males of Skeletal Class III compared to Skeletal Class I

Abdallah S Nouh, HM Abdel Majeed, Essam Mohamed Nassef Selim

Published: October 01, 2021.

Abstract
Objective: Smile plays a vital role in facial appearance. The current study was performed to evaluate the smile parameter variations between Class I and Class III male subjects aiming to obtain a full understanding to smile features serving in diagnosis and treatment planning for highest patient satisfaction.
Materials and Methods: This study was performed on 30 skeletal Class III and Class I males. Two frontal digital photographs were taken for each subject, one at rest and the other in the posed smile position. Photographs were uploaded on Photoshop software for standardization and then uploaded on the Digital Smile Design software (DSD) where the actual incisogingival height of the central incisor was used for automatic calibration.
Results: At rest, there was no significant difference for all soft tissue measurements of Class I and Class III males, while on smiling, Class III males tended to have wider smile widths, less incisor display, wider smile width and a higher percentage of non-consonant and flat smile arcs than normal Class I subjects.
Conclusions: The maxillary incisor display for Class I was found to be significantly greater than that for Class III. The smile width and smile height for Class III was found to be significantly greater than that of Class I.

Keywords: Class III males; Esthetics; Malocclusion; Smile

Orthopedic Device and Data Visualization: A Way to Optimize the Therapeutic Process

Gabriele Pontillo, Roberta Angari

Published: October 01, 2021.

Abstract
Medical design may intervene to improve, prolong and save lives. Many health critical problems can be addressed thanks to the power of design, which solutions, developed in academic and business settings, can answer in an innovative way to the needs of patients. It is in this context that is located the ongoing research presented, which is based on the integration between parametric design and data visualization, whose convergence leads to the realisation of medical devices customized on specific morphologies and needs of users and, as well, - thanks to the integration of IoT - capable to record and return data related to the course of the therapeutic advancements, made readable for both patients and doctors. As highlighted by the most recent scientific literature, the development of technological medical devices, able to reduce steps and simplify the doctor/patient relationship, is becoming an important field of research, most of all if we consider the condition of endemic fragility that characterises the contemporary society. In this perspective, the aim of the paper is to introduce the concept and design of orthopedic devices, through the description of the methodology and approaches applied and of the protocol outlined during the research.

Keywords: Medical Design; Parametric Design; Information Design; E-health; Personalized medicine

Using Kitchen Resources and Home Remedies to Cure common Cold

Saba Khan, Sarah Malik

Published: October 01, 2021.

Abstract
For boosting the immune system, to promote optimum health & to reduce the complications or risks of the disease, kitchens ingredients play a significant role. The objective of this study was to find out the popular home remedies for common cold and to modify them for better results. Survey and interview method helped in collecting the field information from the sample of hundred respondents. The most popular remedies were identified and modified by addition of any three more ingredients from the kitchen shelf. The modified recipes were subjected on the sample of twenty-five adults suffering with common cold. Their experiences showed reduced recovery time and better response in improving their general health condition.

Keywords: Common cold; Home remedies; Kitchen ingredients