Growth Factor as Regenerative Materials in Oral Surgery Management of Periapical Lesions

Patroklos Konstantinos Alevizos^1,4, Ioannis Trigkas^1,4, Magda Koskieri^1,4, Stella^1,4, Stavros Tsantis³, Edit Xhanjanka⁴, Lucas Chatzikonstasntis^1,4, Pantelis Kavrulakis^1,4, Johnny Mahfod^1,4, Ioannis P Georgakopoulos^1,2,4 and Alaa Abu Shareia^1,2,4*
¹WAGRO (World Academy of Growth Factors & Stem Cells in Dentistry), Greece
²WAGRO University, USA
³Department of Medical Physics, School of Medicine, University of Patras, Rion, Greece
⁴PgO-UCAM, Catholic University of Murcia, Spain
*Corresponding Author: Professor. Dr. Alaa Abu Shareia. MSc. DSc., WAGRO (World Academy of Growth Factors & Stem Cells in Dentistry), Greece; WAGRO University, USA; PgO-UCAM, Catholic University of Murcia, Spain.

Published: March 19, 2024

DOI: 10.55162/MCMS.06.203

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Abstract  

This research aims to clarify the PRF / CGF membranes and sticky bone preparation together with other platelet concentrates. A few clinical cases will show how sticky bone is together with PRF membranes applicative in different oral surgery indications [1]. Growth Factor are polypeptide hormones or biological factors. They mediate many cellular processes for the various stages of growth. Endodontic therapy, commonly known as root canal treatment, is indeed highly successful in most cases, with success rates typically ranging from 85% to 97%. However, in a minority of cases, symptoms may persist or reoccur despite initial treatment. In such situations, periapical surgery, also referred to as apical surgery or apicoectomy, may be recommended as the next step. Periapical surgery involves accessing the tip of the tooth's root (apex) and removing any infected tissue or lesions in the surrounding area. This procedure is often indicated when conventional root canal treatment has failed, or when there are persistent issues such as chronic periapical lesions or apical periodontitis. During periapical surgery, the endodontist or oral surgeon will make a small incision in the gum tissue near the affected tooth to access the root tip. The infected tissue is then removed, and the tip of the root may be reshaped or sealed to prevent further infection. Finally, the gum tissue is sutured back into place.

Keywords: Autologous platelets concentrate; concentrated growth factor; endodontic surgery; sticky bone

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