Financial Management assists ways to attain the goals and objectives within the academic institutions. People understand the key features of the financial management that includes the organisation, transparency and awareness about the features that operate the institution ethically and legally. Managing the academic finance is effectively a complicated series of monthly and annual administration of finance at different levels. The success of academics initiates the momentum for the flow of funds within and outside the Academic Institutions. However, this is not merely by chance. It requires rigorous designing and executing of the initiatives for and by the key stakeholders. This is the normal misconception that the financial management of the corporate sector organizations is difficult than the Academic Institutions. In general, the versatility of the financial management of the Corporate Sector Industries could be more but depth, uncertainty and complexity of the financial management of Academic Institutions is at par with that Corporate Sector Companies. In both the sectors, the Human Resource element makes the management more dynamic and challenging. In Academics as well, the employees are determined, ambitious and obsessive as well. This calls for the ability to push back and win their support. Management offers opportunities and resources to the employees and other stakeholders. However, there is an impact of the psychology and mind-set on the financial management. All the Stakeholders are crucial for the Academic Institutions even though the financial management gets affected to a large extent by the Top Management and their decision making.

Open-source software has pumped up a revolutionary change in the way the software industry functions. But it has also increased the concerns related to software licensing issues, when we receive, make copies or distribute any software. Generally, a proprietary software license agreement clearly mentions about its transfer of rights to use, modify, copy, distribute or derivative works. But due to a variety of open license standards and their varied impact, sometimes confusion arises for volunteers/open source developers to choose the proper licensing for their software code. In this context, a clear understanding is necessary about the open source licensing issues for the FOSS developers, enthusiasts and volunteers [1].

Currently, palliative care has become very important in terms of increasing the quality of life of patients , and palliative care based on the Bow Ttie model has become particularly important in recent years. The purpose is the investigate the impact of early palliative care based on the Bow-Tai model on the quality of life of chronic patients.

Bimaxillary protrusion is a commonly seen deformity in Asian populations. This condition is characterized by protusive and proclined upper and lower incisors and incompetence of lips, gummy smile, mentalis muscle strain and anterior open bite [1]. This condition poses a serious threat to the aesthetic concern of the patient which is interwined with psychological trauma and social inter-relation disturbances. A Successful treatment depends on the thorough evaluation of the condition, understanding the need and the concern of the patient and providing an appropriate treatment plan. This case report describes correcting a bimaxillary protrusion by treating the upper anteriors with Root Canal Treatment, placing a post and core with change in the angle of inclination and restoring them with a crown & bridge prosthesis.

Dental implants play a very important role in dentistry. A very careful diagnosis and treatment planning must be followed to grant a successful outcome. It must be taken into consideration the challenges of oral cavity and its anatomical structures and in the maxilla, the maxillary sinus is the most important in this situation.
Keywords: dental implant; maxillary sinus

Anxiety and apprehension of the dental pain tends to avoid the dental treatment. As per the particular requirements of the patient, an ambit of local anesthetics drugs is customized to control the dental pain. Hence, gaining a perception of the aspect of local anesthetics and the knowledge to deliver anesthetic injection techniques correctly is an essential prospect of the Oral Surgery curriculum[1]. Every faculty should go through learning module schedule of the subject topics which is given for the SCORE Learning management system [LMS] module [2].

To live a healthy life style and be free from diseases, fruits must be incorporated in one’s daily food. Fruits are of high nutritional value and provide the body with the required daily allowance. They are highly perishable, but can be made into different products to make them available all year round. They can be processed into products which includes; fruit juice, jellies, marmalades, candies, fruit bars and jams. This study analyses jam produced using date powder and compared it with commercial jam produced using table sugar. The percentage compositions of the blends considered were 50%:50%; 70%:30%; 30%:70% of orange and apple pulps respectively with constant amount of date powder (50%). In addition to the pulp blends, 2.9% commercial pectin was added together with citric acid, and date powder. The entire mixture was heated at 120°C for 25 mins to enhance the viscosity of the blends. Proximate, microbial, physico-chemical analyses, sensory evaluation and Vitamin constituents of the experimental samples and the commercial jam were evaluated. The commercial jam was found best having higher scores in all the sensory parameters. However, in respect to proximate composition, the experimental samples had the highest in protein, ash, moisture, and fibre while the commercial jam only scored high in fat, carbohydrate. In respect to microbial count minimum fungal and bacterial growth, 1.00 cfu X 103 g-1 and 1.00 cfu X 105 g-1 respectively were recorded in the experimental samples at 3 weeks after production. The control sample had the highest value in vitamin A content (130.35mg/100g) and the least in vitamin C content (1.64mg/100g).The nutritional analysis and sensory evaluation obtained proved that the orange and apple jam samples made with date powder is a promising functional product which can be consumed by both young and adults.
Keywords: Orange; Apple; Date; Jam; Composite; Nutritional properties; Sensory analysis

Polyphenols are a large category of chemicals that include phenolic acids, flavonoids, and many other compounds. They have piqued the interest of both society and industry in food production. These chemicals are well-known for their antioxidant properties and potential health advantages, such as anti-inflammatory properties and the prevention of diet-related chronic diseases like cardiovascular disease, neurodegenerative disease, type 2 diabetes, and cancer. However, they have a low bioavailability, which limits their applicability due to their instability during digestion, which is caused by pH, enzymes, and interactions with other nutrients, among
other factors (Bamba et al., 2018).

Objective Confirm the exploratory factorial structure of an explanatory model of the conformation of community health networks before risk events.
Method Two non-experimental, cross-sectional and correlational studies were carried out with non-probabilistic selections of 107 students for the first job and 101 users of community health services for the second research, considering the professional practices and the social service of the first ones, as well as Access to services by the second group.
Results In the first study, the instrument was validated and in the second, the three dimensions reported in the consulted literature were confirmed.
Conclusion The design of the research limits the findings to the scenarios and the study samples, suggesting the extension of the work to other contexts for the contribution of empirical support to the proposed model.
Keywords: Governance; health; model; intervention; network

The present study investigated microbial diversity in the hindgut microbiota of Odontotermes obesus(Rambur). Colonies were isolated both aerobically and anaerobically by using tryptic soy agar medium. Isolates were characterized and identified by means of biochemical tests. Based on tentative identification, all the isolates belonged to the Enterobacteriaceae family. All the colonies were screened for cellulase, amylase and invertase activity. Enzyme assays were performed for positive colonies. The enzyme assay for amylase activity was found to be highest for strain No.16 at 1.46 the highest invertase activity was found in strain No.17 at 1.332 the enzyme assay for cellulase activity was found to be highest for strain No.12 at 0. 09 The results showed that termite gut bacteria play a significant role in biofuel production in terms of plant decomposition and conversion to simple sugars.
Keywords: Odontotermes obesus; Enterobacteriacae; cellulose; amylase; invertase

Ozone is a significant concern for our environment today. The ozone molecule, outside of the ozone layer, is Harmful to the air quality. It also affects humans in a wrong way. Various works are going on to stop the depletion of ozone.
A remarkable improvement was seen, which can predict ozone level three days ahead with accuracy up to 3 days advance. Random Forest and Multivariate Adaptive Regression Splines are some models used for research.
The new AI system developed could cause improved ways to regulate serious ozone problems and even contribute to solutions for global climate change issues. The research team used a singular loss function in developing the machine learning algorithm.
This could help make the planet secure.

Gene therapy is a fantastic new technology that has opened up a plethora of options to treat or prevent previously untreatable diseases. Gene therapy is the use of nucleic acids (either DNA or RNA) is used to  manipulate the genetic information of a patient’s cells. This is particularly helpful for diseases like Cystic Fibrosis where the ability to add a gene that makes the protein product the patient lacks or to just the gene itself is ideal. The addition of CRISPR-Cas for easier and more streamlined gene editing has also been a boon. However, the unfortunate truth is that despite decades of research, only a few gene therapies have made it to market. One of those reasons is the problems with carriers of gene therapy. For over three decades viral vectors were considered the go to for gene therapy carriers however they aggravate the immune system and can cause unwanted genotoxicity. This compromises their usefulness as a therapeutic treatment or preventative. So other methods of gene therapy carriers have been considered. Nanotech deliverers such as exosomes, gold nanoparticles, and others have shown great promise of being able to transport gene therapy with mitigated or no toxicity to the patient. This review will briefly go over both viral vector and nanotech non-viral vector alternatives to delivery of gene therapy.
Keywords: Gene therapy; nanotechnology; gene delivery; CRISPR; exosomes; viruses; magnetosomes

Transdermal drug delivery refers to the drug administration route through the skin that achieves the local or systemic treatment approved for clinical use. It is the third-largest drug delivery system after oral administration and injection. The advantages of the transdermal route are that the administration route of the drug is convenient and could reduce the fluctuation of blood drug concentration and toxic side effects. What is more, the drug could bypass the first-pass side-effect of the liver to prevent the drug from being destroyed in the gastrointestinal tract. Invasomes are new modified liposomes that differ from the liposomal vesicles in that they contain essential volatile oils, which are called terpenes. Also, ethanol in a low percentage is present in the vesicle either in the phospholipid layer or in the hydrous core. These modified newly discovered vesicles are intended to be used for topical and transdermal drug delivery due to their permeation effect and high deformability as compared to transferosomes.
Keywords: Invasomes; Transdermal drug delivery; phospholipids; terpenes; deformable vesicles

Design and use of enzyme inhibitors against viral enzymes is one of the new and effective ways to control viruses and treat viral infections, Enzyme inhibitors inactivate these enzymes by binding to the nucleotides functional groups of the virus vital enzymes, thus can directly disrupt the virus replication cycle and indirectly prevent the spread of viral infections by reducing and controlling the population and number of viruses, these inhibitors, on the one hand, inhibit the virus by filling and Occupying the active sites of the enzyme and on the other hand, they change the stereochemistry of the enzyme by binding to the structure of the enzyme, for this reasons, they are used as an effective and complementary drug in the treatment of infections and viral diseases. Human Immunodeficiency Virus (HIV) is a retrovirus because it has the reverse transcriptase enzyme. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) are a class of Antiretroviral HIV drugs. Non- ucleoside Reverse Transcriptase Inhibitors (NNRTIs) block HIV reverse transcriptase enzymes by connecting to it. Tetrazole derivatives have strong antiviral activity against efavirenz and nevirapine-resistance viruses that have different genetic mutations. In this research, we study NNRTIs function and overview synthesis of 5-aryloxy- etrazole derivatives in the development path of NNRTIs.
Keywords: Anti-HIV Drugs; NNRTIs; Tetrazole; HAART; Retrovirus; Reverse Transcriptase Enzyme 

Therapeutic bioengineering is a rapidly growing discipline in medical science that combines biology and medicine with engineering principles to create products and methods that can tackle the widest range of a variety of medical and health-related issues in today’s society