Antibiotic Stewardship
Madhavi Thara*
Department of Periodontology, Kerala University of Health Sciences, India
*Corresponding Author: Madhavi Thara, Department of Periodontology, Kerala University of Health Sciences, India.
Published: February 26, 2024
DOI: 10.55162/MCMS.06.196
Abstract
Antimicrobial resistance increases morbidity and mortality for individual patients as well as pose a threat to public health. Antimicrobial resistance threatens human, animal and environmental health, killing at least 1.27 million people worldwide and is associated with nearly 5 million deaths in 2019 [1, 2]. The widespread and often inappropriate use of antibiotics is the root cause of antimicrobial resistance and it needs to be addressed urgently [3].
Drug resistance is a consequence of the evolution of microorganisms in the presence of antibiotics. The resistance is inevitable, but the pace and extent of propagation of resistant organisms can be governed by monitoring antibiotic consumption by humans and animals, hygiene, sanitation and infection control [3]. Global Antimicrobial Resistance and Use Surveillance System (GLASS) reported that ciprofloxacin resistance varies from 8.4%-92.9% for Escherichia coli and 4.1%-79.4% for Klebsiella pneumoniae. Additionally, colistin-resistant bacteria have been found in numerous locations, and are producing diseases with no effective antibiotic treatment [3, 4].
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