Immune Response to Rheumatoid Arthritis Inflammation and Mesenchymal Stem Cell Influence on Inflammatory Response
Maral Bishehkolaei, Kevin Sneed and Yashwant Pathak*
Taneja College of Pharmacy, University of South Florida, Tampa Florida, USA
*Corresponding Author: Yashwant Pathak, Taneja College of Pharmacy, University of South Florida, Tampa Florida, USA.
Published: January 21, 2023
DOI: 10.55162/MCMS.04.100
Abstract
Rheumatoid arthritis (RA) is triggered by a series of immune responses to an acute inflammation. The failure of the initial immune response to control the inflammation leads to a chronic inflammatory condition. In which case the loop of positive feedback of immune cells is triggered. This abnormal immune response leads to its classification as an autoimmune disease. Mesenchymal stem cells (MSC) are a self-regenerative, multilineage stem cells that have an immunosuppressive nature. These qualities make them a great candidate for the treatment of autoimmune disorders, specifically RA. RA is a genetically inherited marker that cannot be changed. However, studying the immune response to this inflammatory condition along with the influence of MSC on immune cells can direct us towards a new regenerative drug that can reverse or antagonize the damage caused in advanced cases of RA.