Atorvastatin Induced Constipation

B Akhila sai¹*, Anusha Yadagani², Mounika Maduri³ and Avanish Illuri³

Published: June 30, 2022

DOI: 10.55162/MCMS.03.053

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Abstract  

A 72-year-old with high cholesterol levels (Hypercholesteremia) was advised to take Atorvastatin 20 mg (Atorva-20 mg) which led to constipation and abdominal discomfort. As management, the Atorvastatin was discontinued and replaced with Rosuvastatin. The symptoms of constipation were reduced after cessation of the suspect drug Atorvastatin. The possible mechanisms for the event were unknown but has some proposed mechanisms like1. Levels of Nitric oxide 2. Inhibiting the production of melvonic acid 3. Decrease in coenzyme Q10.

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