A Comparative Assessment of Remineralization Potential of Sodium Fluoride (Naf) And Poly Amido Amine (Pamam) on Artificial Caries Like Lesion of Enamel - An In Vitro Study

Varsha Deokar¹*, Mandakini S Mandale², Jayanti G Humbe², Vaishali A Nandkhedkar², Savita P Wagh² and Poonam R Zanwar^2
1Dental Surgeon, Department Oral Pathology and Microbiology, Govt Dental College & Hospital, Aurangabad
²Associate Professor, Department Oral Pathology and Microbiology, Govt Dental College & Hospital, Aurangabad
*Corresponding Author: Varsha Deokar, Dental Surgeon, Department Oral Pathology and Microbiology, Govt Dental College & Hospital, Aurangabad.

Published: November 17, 2023

DOI: 10.55162/MCDS.03.058

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Abstract  

Dental caries is a continuous process, involving various cycles of demineralization and remineralization. Initial caries can be prevented or arrested by simple and cost effective interventions like with proper plaque control and remineralization therapy. Hence the study is performed with mineralizing agent like NaF and PAMAM. Aim and objectives - To compare the difference in vicker’s hardness number (VHN) of artificial caries like lesion of enamel before and after remineralization with 10% NaF and PAMAM-NH2. Study Design: Experimental randomized analytical- in vitro study. Materials and method - Artificial caries-like lesions were prepared on orthodontically extracted premolars and micro hardness was measured. The samples were divided into two group and subjected to 7 days pH cycle with 10% NaF and PAMAM respectively. Micro hardness was recorded & Obtained micro hardness values were analyzed. Results - The mean difference in increase of micro hardness of the two groups was 8.267VHN which was statistically significant with p value 0.020 (p<0.001) which indicate that PAMAM pre-treatment has greater potential of than pre-treatment with 10% NaF. Conclusion - PAMAM-NH2 can be used as pre-treatment regimen before remineralization.

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